I was looking through the new protocol for EHC(Emergency hormonal contraception) from the Torbay NHS Care Trust. I found something useful and worth sharing. It’s the list of Hepatic Enzyme Inducing Drugs, I’v always wanted to come up with a list myself, but I just havn’t got to it. This group of drugs accelerates metabolism and reduces the efficacy of many drugs especially drugs with a narrow therapeutic window i.e theophylline, it is also important to know that they do the same for contraceptive steroids. I think the 1st few on the list are the more common List of hepatic enzyme inducing drugs .
- Carbamazepine
- Griseofulvin
- Phenytoin
- Rifampicin
- St John’s Wort
- Barbiturates
- Modafinil
- Topiramate
- Primidone
- Tacrolimus
- Oxcarbazepine
- Ritonavir
- Rifabutin
- Bosentan
- Certain PPI
- Certain HIV drugs
For me, I try to remember the 5 that are highlighted in red, to make it easier, I came up with an acronym – C-GPRS, hope that was helpful!! Leave a comment to add any others to the list!